inotropic effect meaning in Hindi

Examples

1. Endothelin receptor activation mediates strong pulmonary vasoconstriction and positive inotropic effect on the heart.
2. Disopyramide has a negative inotropic effect on the ventricular myocardium, significantly decreasing the contractility.
3. Antianginal effects result from negative chronotropic and inotropic effects, which decrease cardiac workload and oxygen demand.
4. Hypercalcemia can result in an increase in heart rate and a positive inotropic effect ( increase in contractility ).
5. Calcium channel blockers are generally contraindicated due to their negative inotropic effect, particularly in cardiomyopathy caused by amyloidosis.
6. The calcium channel blockers typically used are verapamil and diltiazem, because of their combined vasodilator and negative inotropic effects.
7. The parasympathetic nervous system, through the action of vagus nerve, exerts a negative inotropic effect upon the heart.
8. Because of the negative inotropic effects, the nondihydropyridine calcium channel blockers should be avoided ( or used with caution ) in individuals with cardiomyopathy.
9. The primary antihypertensive mechanism of beta blockers is unclear, but may involve reduction in cardiac output ( due to negative chronotropic and inotropic effects ).
10. Onmel / Sporanox ( Itraconazole ) exhibits a negative inotropic effect on the heart and thus could spur an additive effect when used concomitantly with Isradipine.